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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク ornithine decarboxylase antizyme ： ウィキペディア英語版 ornithine decarboxylase antizyme In molecular biology, Ornithine decarboxylase antizyme (ODC-AZ) is an ornithine decarboxylase inhibitor. It binds to, and destabilises, ornithine decarboxylase (ODC), a key enzyme in polyamine synthesis. ODC is then rapidly degraded. It was first characterized in 1981. The expression of ODC-AZ requires programmed, ribosomal frameshifting which is modulated according to the cellular concentration of polyamines. High levels of polyamines induce a +1 ribosomal frameshift in the translation of mRNA for the antizyme leading to the expression of a full-length protein. At least two forms of ODC-AZ exist in mammals and the protein has been found in Drosophila (protein Gutfeeling) as well as in Saccharomyces yeast (encoded by the OAZ1 gene).〔(SGD entry for OAZ1 gene )〕 Human genes encoding Ornithine decarboxylase antizymes are OAZ1, OAZ2, and OAZ3. ==References== 〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「ornithine decarboxylase antizyme」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.